Context dependent function of APPb enhancer identified using enhancer trap-containing BACs as transgenes in zebrafish

An enhancer within intron 1 of the amyloid precursor protein gene (APPb) of zebrafish is identified functionally using a novel approach. Bacterial artificial chromosomes (BACs) were retrofitted with enhancer traps, and expressed as transgenes in zebrafish. Expression from both transient assays and s...

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Detalles Bibliográficos
Autores principales: Shakes, Leighcraft A., Malcolm, Tennison L., Allen, Kevin L., De, Supriyo, Harewood, Ken R., Chatterjee, Pradeep K.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577333/
https://www.ncbi.nlm.nih.gov/pubmed/18832376
http://dx.doi.org/10.1093/nar/gkn628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577333/
https://www.ncbi.nlm.nih.gov/pubmed/18832376
http://dx.doi.org/10.1093/nar/gkn628

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