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Context dependent function of APPb enhancer identified using enhancer trap-containing BACs as transgenes in zebrafish
An enhancer within intron 1 of the amyloid precursor protein gene (APPb) of zebrafish is identified functionally using a novel approach. Bacterial artificial chromosomes (BACs) were retrofitted with enhancer traps, and expressed as transgenes in zebrafish. Expression from both transient assays and s...
Autores principales: | Shakes, Leighcraft A., Malcolm, Tennison L., Allen, Kevin L., De, Supriyo, Harewood, Ken R., Chatterjee, Pradeep K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577333/ https://www.ncbi.nlm.nih.gov/pubmed/18832376 http://dx.doi.org/10.1093/nar/gkn628 |
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