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How PspGI, catalytic domain of EcoRII and Ecl18kI acquire specificities for different DNA targets

Restriction endonucleases Ecl18kI and PspGI/catalytic domain of EcoRII recognize CCNGG and CCWGG sequences (W stands for A or T), respectively. The enzymes are structurally similar, interact identically with the palindromic CC:GG parts of their recognition sequences and flip the nucleotides at their...

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Detalles Bibliográficos
Autores principales:	Tamulaitis, Gintautas, Zaremba, Mindaugas, Szczepanowski, Roman H., Bochtler, Matthias, Siksnys, Virginijus
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577355/ https://www.ncbi.nlm.nih.gov/pubmed/18820295 http://dx.doi.org/10.1093/nar/gkn621

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