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The clinicopathological and prognostic impact of 14-3-3 sigma expression on vulvar squamous cell carcinomas

BACKGROUND: 14-3-3 sigma (σ) promotes G2/M cell cycle arrest by sequestering cyclin B1-CDC2 complex in cytoplasm. Down-regulation of 14-3-3σ, which has been demonstrated in various carcinomas, may contribute to malignant transformation. However, the exact role of 14-3-3σ in the pathogenesis of vulva...

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Detalles Bibliográficos
Autores principales:	Wang, Zhihui, Tropè, Claes G, Suo, Zhenhe, Trøen, Gunhild, Yang, Guanrui, Nesland, Jahn M, Holm, Ruth
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577690/ https://www.ncbi.nlm.nih.gov/pubmed/18950492 http://dx.doi.org/10.1186/1471-2407-8-308

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