Cargando…
Cigarette Smoking, Birthweight and Osteoporosis in Adulthood: Results from the Hertfordshire Cohort Study
We looked for interaction between early environment and adult lifestyle in determination of bone mineral content (BMC) and bone mineral density (BMD) among 498 men and 468 women for whom birth records were available. Participants completed a health questionnaire, and bone densitometry (DXA) of the l...
Autores principales: | , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577951/ https://www.ncbi.nlm.nih.gov/pubmed/19088869 http://dx.doi.org/10.2174/1874312900802010033 |
_version_ | 1782160521089253376 |
---|---|
author | Moinuddin, M.M Jameson, K.A Syddall, H.E Sayer, A. Aihie Martin, H.J Robinson, S Cooper, C Dennison, E.M |
author_facet | Moinuddin, M.M Jameson, K.A Syddall, H.E Sayer, A. Aihie Martin, H.J Robinson, S Cooper, C Dennison, E.M |
author_sort | Moinuddin, M.M |
collection | PubMed |
description | We looked for interaction between early environment and adult lifestyle in determination of bone mineral content (BMC) and bone mineral density (BMD) among 498 men and 468 women for whom birth records were available. Participants completed a health questionnaire, and bone densitometry (DXA) of the lumbar spine and femoral neck performed. We found no relationships between cigarette and alcohol consumption, physical activity and either BMC or BMD after adjustment for age, body mass index, dietary calcium, social class, HRT use and years since menopause. However, male current smokers in the lowest third of birth weight had lower femoral neck BMD than ex- or never smokers from the lowest birth weight third (p value for interaction term = 0.04). Similar trends were seen with femoral neck BMC and lumber spine BMC.Individuals of lower birth weight may be particularly vulnerable to the effects of bone noxious stimuli such as cigarette smoking. |
format | Text |
id | pubmed-2577951 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | Bentham Open |
record_format | MEDLINE/PubMed |
spelling | pubmed-25779512008-12-16 Cigarette Smoking, Birthweight and Osteoporosis in Adulthood: Results from the Hertfordshire Cohort Study Moinuddin, M.M Jameson, K.A Syddall, H.E Sayer, A. Aihie Martin, H.J Robinson, S Cooper, C Dennison, E.M Open Rheumatol J Article We looked for interaction between early environment and adult lifestyle in determination of bone mineral content (BMC) and bone mineral density (BMD) among 498 men and 468 women for whom birth records were available. Participants completed a health questionnaire, and bone densitometry (DXA) of the lumbar spine and femoral neck performed. We found no relationships between cigarette and alcohol consumption, physical activity and either BMC or BMD after adjustment for age, body mass index, dietary calcium, social class, HRT use and years since menopause. However, male current smokers in the lowest third of birth weight had lower femoral neck BMD than ex- or never smokers from the lowest birth weight third (p value for interaction term = 0.04). Similar trends were seen with femoral neck BMC and lumber spine BMC.Individuals of lower birth weight may be particularly vulnerable to the effects of bone noxious stimuli such as cigarette smoking. Bentham Open 2008-05-06 /pmc/articles/PMC2577951/ /pubmed/19088869 http://dx.doi.org/10.2174/1874312900802010033 Text en © Moinuddin et al.; Licensee Bentham Open. http://creativecommons.org/licenses/by/2.5/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.5/), which permits unrestrictive use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Article Moinuddin, M.M Jameson, K.A Syddall, H.E Sayer, A. Aihie Martin, H.J Robinson, S Cooper, C Dennison, E.M Cigarette Smoking, Birthweight and Osteoporosis in Adulthood: Results from the Hertfordshire Cohort Study |
title | Cigarette Smoking, Birthweight and Osteoporosis in Adulthood: Results from the Hertfordshire Cohort Study |
title_full | Cigarette Smoking, Birthweight and Osteoporosis in Adulthood: Results from the Hertfordshire Cohort Study |
title_fullStr | Cigarette Smoking, Birthweight and Osteoporosis in Adulthood: Results from the Hertfordshire Cohort Study |
title_full_unstemmed | Cigarette Smoking, Birthweight and Osteoporosis in Adulthood: Results from the Hertfordshire Cohort Study |
title_short | Cigarette Smoking, Birthweight and Osteoporosis in Adulthood: Results from the Hertfordshire Cohort Study |
title_sort | cigarette smoking, birthweight and osteoporosis in adulthood: results from the hertfordshire cohort study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577951/ https://www.ncbi.nlm.nih.gov/pubmed/19088869 http://dx.doi.org/10.2174/1874312900802010033 |
work_keys_str_mv | AT moinuddinmm cigarettesmokingbirthweightandosteoporosisinadulthoodresultsfromthehertfordshirecohortstudy AT jamesonka cigarettesmokingbirthweightandosteoporosisinadulthoodresultsfromthehertfordshirecohortstudy AT syddallhe cigarettesmokingbirthweightandosteoporosisinadulthoodresultsfromthehertfordshirecohortstudy AT sayeraaihie cigarettesmokingbirthweightandosteoporosisinadulthoodresultsfromthehertfordshirecohortstudy AT martinhj cigarettesmokingbirthweightandosteoporosisinadulthoodresultsfromthehertfordshirecohortstudy AT robinsons cigarettesmokingbirthweightandosteoporosisinadulthoodresultsfromthehertfordshirecohortstudy AT cooperc cigarettesmokingbirthweightandosteoporosisinadulthoodresultsfromthehertfordshirecohortstudy AT dennisonem cigarettesmokingbirthweightandosteoporosisinadulthoodresultsfromthehertfordshirecohortstudy |