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Prognostic implication of p27(Kip1), Skp2 and Cks1 expression in renal cell carcinoma: a tissue microarray study
BACKGROUND: p27(Kip1 )plays a major role as a negative regulator of the cell cycle. The regulation of p27(Kip1 )degradation is mediated by its specific ubiquitin ligase subunits S-phase kinase protein (Skp) 2 and cyclin-dependent kinase subunit (Cks) 1. However, little is known regarding the prognos...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579281/ https://www.ncbi.nlm.nih.gov/pubmed/18922157 http://dx.doi.org/10.1186/1756-9966-27-51 |