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Evolutionary history of histone demethylase families: distinct evolutionary patterns suggest functional divergence
BACKGROUND: Histone methylation can dramatically affect chromatin structure and gene expression and was considered irreversible until recent discoveries of two families of histone demethylases, the KDM1 (previously LSD1) and JmjC domain-containing proteins. These two types of proteins have different...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579438/ https://www.ncbi.nlm.nih.gov/pubmed/18950507 http://dx.doi.org/10.1186/1471-2148-8-294 |