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Identification of hot-spot residues in protein-protein interactions by computational docking

BACKGROUND: The study of protein-protein interactions is becoming increasingly important for biotechnological and therapeutic reasons. We can define two major areas therein: the structural prediction of protein-protein binding mode, and the identification of the relevant residues for the interaction...

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Detalles Bibliográficos
Autores principales: Grosdidier, Solène, Fernández-Recio, Juan
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579439/
https://www.ncbi.nlm.nih.gov/pubmed/18939967
http://dx.doi.org/10.1186/1471-2105-9-447

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