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Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
BACKGROUND: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models assume the statistical independence of each position in the sequence, but the energetics of protein folding is better cap...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579440/ https://www.ncbi.nlm.nih.gov/pubmed/18847485 http://dx.doi.org/10.1186/1471-2105-9-429 |