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Reduction of DILP2 in Drosophila Triages a Metabolic Phenotype from Lifespan Revealing Redundancy and Compensation among DILPs

The insulin/IGF-like signalling (IIS) pathway has diverse functions in all multicellular organisms, including determination of lifespan. The seven insulin-like peptides (DILPs) in Drosophila are expressed in a stage- and tissue-specific manner. Partial ablation of the median neurosecretory cells (mN...

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Detalles Bibliográficos
Autores principales:	Broughton, Susan, Alic, Nazif, Slack, Cathy, Bass, Timothy, Ikeya, Tomoatsu, Vinti, Giovanna, Tommasi, Anna Maria, Driege, Yasmine, Hafen, Ernst, Partridge, Linda
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579582/ https://www.ncbi.nlm.nih.gov/pubmed/19005568 http://dx.doi.org/10.1371/journal.pone.0003721

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