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Phylogenetic Dependency Networks: Inferring Patterns of CTL Escape and Codon Covariation in HIV-1 Gag

HIV avoids elimination by cytotoxic T-lymphocytes (CTLs) through the evolution of escape mutations. Although there is mounting evidence that these escape pathways are broadly consistent among individuals with similar human leukocyte antigen (HLA) class I alleles, previous population-based studies ha...

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Detalles Bibliográficos
Autores principales: Carlson, Jonathan M., Brumme, Zabrina L., Rousseau, Christine M., Brumme, Chanson J., Matthews, Philippa, Kadie, Carl, Mullins, James I., Walker, Bruce D., Harrigan, P. Richard, Goulder, Philip J. R., Heckerman, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579584/
https://www.ncbi.nlm.nih.gov/pubmed/19023406
http://dx.doi.org/10.1371/journal.pcbi.1000225