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Phylogenetic Dependency Networks: Inferring Patterns of CTL Escape and Codon Covariation in HIV-1 Gag
HIV avoids elimination by cytotoxic T-lymphocytes (CTLs) through the evolution of escape mutations. Although there is mounting evidence that these escape pathways are broadly consistent among individuals with similar human leukocyte antigen (HLA) class I alleles, previous population-based studies ha...
Autores principales: | Carlson, Jonathan M., Brumme, Zabrina L., Rousseau, Christine M., Brumme, Chanson J., Matthews, Philippa, Kadie, Carl, Mullins, James I., Walker, Bruce D., Harrigan, P. Richard, Goulder, Philip J. R., Heckerman, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579584/ https://www.ncbi.nlm.nih.gov/pubmed/19023406 http://dx.doi.org/10.1371/journal.pcbi.1000225 |
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