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Downregulation of HLA Class I molecules in the tumour is associated with a poor prognosis in patients with oesophageal squamous cell carcinoma

As antigenic peptides in the context of human leukocyte antigen (HLA) class I molecules are recognised by cytotoxic T lymphocytes (CTL), the downregulation of HLA class I molecules is one of the reasons why tumour cells can evade CTL-mediated anti-tumour immunity. In this study, we investigated HLA...

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Detalles Bibliográficos
Autores principales:	Mizukami, Y, Kono, K, Maruyama, T, Watanabe, M, Kawaguchi, Y, Kamimura, K, Fujii, H
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2008
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579690/ https://www.ncbi.nlm.nih.gov/pubmed/18841157 http://dx.doi.org/10.1038/sj.bjc.6604715

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