Profile Comparer: a program for scoring and aligning profile hidden Markov models

Summary: Profile Comparer (PRC) is a stand-alone program for scoring and aligning profile hidden Markov models (HMMs) of protein families. PRC can read models produced by SAM and HMMER, two popular profile HMM packages, as well as PSI-BLAST checkpoint files. This application note provides a brief de...

Descripción completa

Detalles Bibliográficos
Autor principal: Madera, Martin
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2579712/
https://www.ncbi.nlm.nih.gov/pubmed/18845584
http://dx.doi.org/10.1093/bioinformatics/btn504
Descripción
Sumario:Summary: Profile Comparer (PRC) is a stand-alone program for scoring and aligning profile hidden Markov models (HMMs) of protein families. PRC can read models produced by SAM and HMMER, two popular profile HMM packages, as well as PSI-BLAST checkpoint files. This application note provides a brief description of the profile–profile algorithm used by PRC. Availability: The C source code licensed under the GNU General Public Licence and Linux and Mac OS X binaries can be downloaded from http://supfam.org/PRC. Contact: martin.madera@gmail.com Supplementary information: Supplementary data are available at Bioinformatics online.

Ejemplares similares