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GC Content Increased at CpG Flanking Positions of Fish Genes Compared with Sea Squirt Orthologs as a Mechanism for Reducing Impact of DNA Methylation
BACKGROUND: Fractional DNA methylation in sea squirts evolved to global DNA methylation in fish. The impact of global DNA methylation is reflected by more CpG depletions and/or more A/T to G/C changes at CpG flanking positions due to context-dependent mutations of methylated CpG sites. METHODS AND F...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
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Public Library of Science
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580031/ https://www.ncbi.nlm.nih.gov/pubmed/19005573 http://dx.doi.org/10.1371/journal.pone.0003612 |