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uPA is upregulated by high dose celecoxib in women at increased risk of developing breast cancer

BACKGROUND: While increased urokinase-type plasminogen activator (uPA) expression in breast cancer tissue is directly associated with poor prognosis, recent evidence suggests that uPA overexpression may suppress tumor growth and prolong survival. Celecoxib has been shown to have antiangiogenic and a...

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Detalles Bibliográficos
Autores principales:	Qin, Wenyi, Zhu, Weizhu, Hewett, John E, Rottinghaus, George, Chen, Yin-Chieh, Flynn, John T, Kliethermes, Beth, Mannello, Ferdinando, Sauter, Edward R
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2580770/ https://www.ncbi.nlm.nih.gov/pubmed/18922176 http://dx.doi.org/10.1186/1471-2407-8-298

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