Cargando…

Inactive and Active States of the Interferon-inducible Resistance GTPase, Irga6, in Vivo

Irga6, a myristoylated, interferon-inducible member of the immunity-related GTPase family, contributes to disease resistance against Toxoplasma gondii in mice. Accumulation of Irga6 on the T. gondii parasitophorous vacuole membrane is associated with vesiculation and ultimately disruption of the vac...

Descripción completa

Detalles Bibliográficos
Autores principales:	Papic, Natasa, Hunn, Julia P., Pawlowski, Nikolaus, Zerrahn, Jens, Howard, Jonathan C.
Formato:	Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2008
Materias:	Molecular Basis of Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581590/ https://www.ncbi.nlm.nih.gov/pubmed/18784077 http://dx.doi.org/10.1074/jbc.M804846200

Ejemplares similares

The activation mechanism of Irga6, an interferon-inducible GTPase contributing to mouse resistance against Toxoplasma gondii
por: Pawlowski, Nikolaus, et al.
Publicado: (2011)

Regulatory interactions between IRG resistance GTPases in the cellular response to Toxoplasma gondii
por: Hunn, Julia P, et al.
Publicado: (2008)

The immunity-related GTPase Irga6 dimerizes in a parallel head-to-head fashion
por: Schulte, Kathrin, et al.
Publicado: (2016)

α2β1 Integrin Regulates Lineage Commitment in Multipotent Human Colorectal Cancer Cells
por: Kirkland, Susan C., et al.
Publicado: (2008)

IMC1b Is a Putative Membrane Skeleton Protein Involved in Cell Shape, Mechanical Strength, Motility, and Infectivity of Malaria Ookinetes
por: Tremp, Annie Z., et al.
Publicado: (2008)

Identification and Functional Characterization of an N-terminal Oligomerization Domain for Polycystin-2
por: Feng, Shuang, et al.
Publicado: (2008)

Ectodomain Lysines and Suramin Block of P2X(1) Receptors
por: Sim, Joan A., et al.
Publicado: (2008)

Targeted Disruption of NeuroD, a Proneural Basic Helix-Loop-Helix Factor, Impairs Distal Lung Formation and Neuroendocrine Morphology in the Neonatal Lung
por: Neptune, Enid R., et al.
Publicado: (2008)

Interactions between the Yeast SM22 Homologue Scp1 and Actin Demonstrate the Importance of Actin Bundling in Endocytosis
por: Gheorghe, Dana M., et al.
Publicado: (2008)

The Spindle Checkpoint Functions of Mad3 and Mad2 Depend on a Mad3 KEN Box-mediated Interaction with Cdc20-Anaphase-promoting Complex (APC/C)
por: Sczaniecka, Matylda, et al.
Publicado: (2008)

Regulatory ATPase Sites of Cytoplasmic Dynein Affect Processivity and Force Generation
por: Cho, Carol, et al.
Publicado: (2008)

A Drosophila Model for Amyotrophic Lateral Sclerosis Reveals Motor Neuron Damage by Human SOD1
por: Watson, Melanie R., et al.
Publicado: (2008)

Combinatorial Signals of Activin/Nodal and Bone Morphogenic Protein Regulate the Early Lineage Segregation of Human Embryonic Stem Cells
por: Wu, Zhao, et al.
Publicado: (2008)

Roles of STAT3/SOCS3 Pathway in Regulating the Visual Function and Ubiquitin-Proteasome-dependent Degradation of Rhodopsin during Retinal Inflammation
por: Ozawa, Yoko, et al.
Publicado: (2008)

Caspase 8 Promotes Peripheral Localization and Activation of Rab5
por: Torres, Vicente A., et al.
Publicado: (2008)

Phosphorylation of p53 Is Regulated by TPX2-Aurora A in Xenopus Oocytes
por: Pascreau, Gaetan, et al.
Publicado: (2009)

Nuclear Factor Y Is Required for Basal Activation and Chromatin Accessibility of Fibroblast Growth Factor Receptor 2 Promoter in Osteoblast-like Cells
por: Sun, Fenyong, et al.
Publicado: (2009)

Real-time Analysis of Conformation-sensitive Antibody Binding Provides New Insights into Integrin Conformational Regulation
por: Chigaev, Alexandre, et al.
Publicado: (2009)

Septin 11 Restricts InlB-mediated Invasion by Listeria
por: Mostowy, Serge, et al.
Publicado: (2009)

MEK5/ERK5 Signaling Modulates Endothelial Cell Migration and Focal Contact Turnover
por: Spiering, Désirée, et al.
Publicado: (2009)

An Essential Role for the Plasmodium Nek-2 Nima-related Protein Kinase in the Sexual Development of Malaria Parasites
por: Reininger, Luc, et al.
Publicado: (2009)

Mammalian SUN Protein Interaction Networks at the Inner Nuclear Membrane and Their Role in Laminopathy Disease Processes
por: Haque, Farhana, et al.
Publicado: (2010)

Annexin-II, DNA, and Histones Serve as Factor H Ligands on the Surface of Apoptotic Cells
por: Leffler, Jonatan, et al.
Publicado: (2010)

Munc18/Syntaxin Interaction Kinetics Control Secretory Vesicle Dynamics
por: Rickman, Colin, et al.
Publicado: (2010)

Dnmt3 and G9a Cooperate for Tissue-specific Development in Zebrafish
por: Rai, Kunal, et al.
Publicado: (2010)

Role for X-linked Inhibitor of Apoptosis Protein Upstream of Mitochondrial Permeabilization
por: Owens, Thomas W., et al.
Publicado: (2010)

Kinome Sirna Screen Identifies SMG-1 as a Negative Regulator of Hypoxia-inducible Factor-1α in Hypoxia
por: Chen, Run-Qiang, et al.
Publicado: (2009)

Erythrocytic Casein Kinase II Regulates Cytoadherence of Plasmodium falciparum-infected Red Blood Cells
por: Hora, Rachna, et al.
Publicado: (2009)

Ror2 Receptor Requires Tyrosine Kinase Activity to Mediate Wnt5A Signaling
por: Mikels, Amanda, et al.
Publicado: (2009)

Identification of Two Critical Amino Acid Residues of the Severe Acute Respiratory Syndrome Coronavirus Spike Protein for Its Variation in Zoonotic Tropism Transition via a Double Substitution Strategy
por: Qu, Xiu-Xia, et al.
Publicado: (2005)

The IFN-γ-Inducible GTPase, Irga6, Protects Mice against Toxoplasma gondii but Not against Plasmodium berghei and Some Other Intracellular Pathogens
por: Liesenfeld, Oliver, et al.
Publicado: (2011)

IFN-γ-Inducible Irga6 Mediates Host Resistance against Chlamydia trachomatis via Autophagy
por: Al-Zeer, Munir A., et al.
Publicado: (2009)

In vivo Functional Genomics for Undiagnosed Patients: The Impact of Small GTPases Signaling Dysregulation at Pan-Embryo Developmental Scale
por: Lauri, Antonella, et al.
Publicado: (2021)

Multifaceted Rho GTPase Signaling at the Endomembranes
por: Phuyal, Santosh, et al.
Publicado: (2019)

Multi-Omics Analysis Identifying Key Biomarkers in Ovarian Cancer
por: Li, Ju-Yueh, et al.
Publicado: (2020)

A Dedicated Promoter Drives Constitutive Expression of the Cell-Autonomous Immune Resistance GTPase, Irga6 (IIGP1) in Mouse Liver
por: Zeng, Jia, et al.
Publicado: (2009)

Targeting Rho GTPase Signaling Networks in Cancer
por: Clayton, Natasha S., et al.
Publicado: (2020)

Editorial: Signaling by Small GTPases in Metastatic Disease
por: Parker, Peter J., et al.
Publicado: (2022)

Editorial: Neuronal cytoskeleton and GTPases in health and diseases
por: Conde, Cecilia, et al.
Publicado: (2022)

X-Inactive-Specific Transcript: Review of Its Functions in the Carcinogenesis
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_t5mktg8a0piq7clnbltg3esidg