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MicroRNA Expression Patterns and Function in Endodermal Differentiation of Human Embryonic Stem Cells

BACKGROUND/AIMS: microRNAs (miRNAs) are small noncoding RNAs that regulate cognate mRNAs post-transcriptionally. Human embryonic stem cells (hESC), which exhibit the characteristics of pluripotency and self-renewal, may serve as a model to study the role of miRNAs in early human development. We aime...

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Detalles Bibliográficos
Autores principales: Tzur, Galit, Levy, Asaf, Meiri, Eti, Barad, Omer, Spector, Yael, Bentwich, Zvi, Mizrahi, Lina, Katzenellenbogen, Mark, Ben-Shushan, Etti, Reubinoff, Benjamin E., Galun, Eithan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581805/
https://www.ncbi.nlm.nih.gov/pubmed/19015728
http://dx.doi.org/10.1371/journal.pone.0003726