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A Critical Role of a Cellular Membrane Traffic Protein in Poliovirus RNA Replication
Replication of many RNA viruses is accompanied by extensive remodeling of intracellular membranes. In poliovirus-infected cells, ER and Golgi stacks disappear, while new clusters of vesicle-like structures form sites for viral RNA synthesis. Virus replication is inhibited by brefeldin A (BFA), impli...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2581890/ https://www.ncbi.nlm.nih.gov/pubmed/19023417 http://dx.doi.org/10.1371/journal.ppat.1000216 |