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Long, Processive Enzymatic Dna Synthesis Using 100% Dye-Labeled Terminal Phosphate-Linked Nucleotides
We demonstrate the efficient synthesis of DNA with complete replacement of the four deoxyribonucleoside triphosphate (dNTP) substrates with nucleotides carrying fluorescent labels. A different, spectrally separable fluorescent dye suitable for single molecule fluorescence detection was conjugated to...
Autores principales: | Korlach, Jonas, Bibillo, Arek, Wegener, Jeffrey, Peluso, Paul, Pham, Thang T., Park, Insil, Clark, Sonya, Otto, Geoff A., Turner, Stephen W. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582155/ https://www.ncbi.nlm.nih.gov/pubmed/18711669 http://dx.doi.org/10.1080/15257770802260741 |
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