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Enhanced A(3 )adenosine receptor selectivity of multivalent nucleoside-dendrimer conjugates

BACKGROUND: An approach to use multivalent dendrimer carriers for delivery of nucleoside signaling molecules to their cell surface G protein-coupled receptors (GPCRs) was recently introduced. RESULTS: A known adenosine receptor (AR) agonist was conjugated to polyamidoamine (PAMAM) dendrimer carriers...

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Detalles Bibliográficos
Autores principales: Klutz, Athena M, Gao, Zhan-Guo, Lloyd, John, Shainberg, Asher, Jacobson, Kenneth A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582240/
https://www.ncbi.nlm.nih.gov/pubmed/18947419
http://dx.doi.org/10.1186/1477-3155-6-12