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c-Myc Is Required for Maintenance of Glioma Cancer Stem Cells

BACKGROUND: Malignant gliomas rank among the most lethal cancers. Gliomas display a striking cellular heterogeneity with a hierarchy of differentiation states. Recent studies support the existence of cancer stem cells in gliomas that are functionally defined by their capacity for extensive self-rene...

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Detalles Bibliográficos
Autores principales: Wang, Jialiang, Wang, Hui, Li, Zhizhong, Wu, Qiulian, Lathia, Justin D., McLendon, Roger E., Hjelmeland, Anita B., Rich, Jeremy N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582454/
https://www.ncbi.nlm.nih.gov/pubmed/19020659
http://dx.doi.org/10.1371/journal.pone.0003769