The confused cancer patient: a case of 5-fluorouracil–induced encephalopathy

The fluorinated pyrimidine 5-fluorouracil (5-fu) is an anticancer agent used in most adjuvant and palliative treatment regimens for colorectal cancer. Neurotoxicities are considered extremely rare side effects of 5-fu. Here, we report a case of 5-fu–induced encephalopathy, manifesting as seizures an...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheung, W.Y., Fralick, R.A., Cheng, S.
Formato: Texto
Lenguaje:English
Publicado: Multimed Inc. 2008
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582518/
https://www.ncbi.nlm.nih.gov/pubmed/19008998
_version_ 1782160679519649792
author Cheung, W.Y.
Fralick, R.A.
Cheng, S.
author_facet Cheung, W.Y.
Fralick, R.A.
Cheng, S.
author_sort Cheung, W.Y.
collection PubMed
description The fluorinated pyrimidine 5-fluorouracil (5-fu) is an anticancer agent used in most adjuvant and palliative treatment regimens for colorectal cancer. Neurotoxicities are considered extremely rare side effects of 5-fu. Here, we report a case of 5-fu–induced encephalopathy, manifesting as seizures and delirium, in an era of oxaliplatin-containing chemotherapy. If ammonia levels are elevated, lactulose may be considered in the initial management of neuropsychiatric complications from 5-fu.
format Text
id pubmed-2582518
institution National Center for Biotechnology Information
language English
publishDate 2008
publisher Multimed Inc.
record_format MEDLINE/PubMed
spelling pubmed-25825182008-11-13 The confused cancer patient: a case of 5-fluorouracil–induced encephalopathy Cheung, W.Y. Fralick, R.A. Cheng, S. Curr Oncol Case Report The fluorinated pyrimidine 5-fluorouracil (5-fu) is an anticancer agent used in most adjuvant and palliative treatment regimens for colorectal cancer. Neurotoxicities are considered extremely rare side effects of 5-fu. Here, we report a case of 5-fu–induced encephalopathy, manifesting as seizures and delirium, in an era of oxaliplatin-containing chemotherapy. If ammonia levels are elevated, lactulose may be considered in the initial management of neuropsychiatric complications from 5-fu. Multimed Inc. 2008-10 /pmc/articles/PMC2582518/ /pubmed/19008998 Text en 2008 Multimed Inc.
spellingShingle Case Report
Cheung, W.Y.
Fralick, R.A.
Cheng, S.
The confused cancer patient: a case of 5-fluorouracil–induced encephalopathy
title The confused cancer patient: a case of 5-fluorouracil–induced encephalopathy
title_full The confused cancer patient: a case of 5-fluorouracil–induced encephalopathy
title_fullStr The confused cancer patient: a case of 5-fluorouracil–induced encephalopathy
title_full_unstemmed The confused cancer patient: a case of 5-fluorouracil–induced encephalopathy
title_short The confused cancer patient: a case of 5-fluorouracil–induced encephalopathy
title_sort confused cancer patient: a case of 5-fluorouracil–induced encephalopathy
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582518/
https://www.ncbi.nlm.nih.gov/pubmed/19008998
work_keys_str_mv AT cheungwy theconfusedcancerpatientacaseof5fluorouracilinducedencephalopathy
AT fralickra theconfusedcancerpatientacaseof5fluorouracilinducedencephalopathy
AT chengs theconfusedcancerpatientacaseof5fluorouracilinducedencephalopathy
AT cheungwy confusedcancerpatientacaseof5fluorouracilinducedencephalopathy
AT fralickra confusedcancerpatientacaseof5fluorouracilinducedencephalopathy
AT chengs confusedcancerpatientacaseof5fluorouracilinducedencephalopathy

Ejemplares similares