A competitive hybridization model predicts probe signal intensity on high density DNA microarrays

A central, unresolved problem of DNA microarray technology is the interpretation of different signal intensities from multiple probes targeting the same transcript. We propose a competitive hybridization model for DNA microarray hybridization. Our model uses a probe-specific dissociation constant th...

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Detalles Bibliográficos
Autores principales: Li, Shuzhao, Pozhitkov, Alex, Brouwer, Marius
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582621/
https://www.ncbi.nlm.nih.gov/pubmed/18931378
http://dx.doi.org/10.1093/nar/gkn740

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582621/
https://www.ncbi.nlm.nih.gov/pubmed/18931378
http://dx.doi.org/10.1093/nar/gkn740

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