Cargando…
A competitive hybridization model predicts probe signal intensity on high density DNA microarrays
A central, unresolved problem of DNA microarray technology is the interpretation of different signal intensities from multiple probes targeting the same transcript. We propose a competitive hybridization model for DNA microarray hybridization. Our model uses a probe-specific dissociation constant th...
Autores principales: | Li, Shuzhao, Pozhitkov, Alex, Brouwer, Marius |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582621/ https://www.ncbi.nlm.nih.gov/pubmed/18931378 http://dx.doi.org/10.1093/nar/gkn740 |
Ejemplares similares
-
Beyond Affymetrix arrays: expanding the set of known hybridization isotherms and observing pre-wash signal intensities
por: Pozhitkov, Alex E., et al.
Publicado: (2010) -
A study of the relationships between oligonucleotide properties and hybridization signal intensities from NimbleGen microarray datasets
por: Wei, Hairong, et al.
Publicado: (2008) -
Tests of rRNA hybridization to microarrays suggest that hybridization characteristics of oligonucleotide probes for species discrimination cannot be predicted
por: Pozhitkov, Alex, et al.
Publicado: (2006) -
Development and application of a DNA microarray-based yeast two-hybrid system
por: Suter, Bernhard, et al.
Publicado: (2013) -
Estimating the proportion of microarray probes expressed in an RNA sample
por: Shi, Wei, et al.
Publicado: (2010)