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In vivo evaluation of PhiC31 recombinase activity using a self-excision cassette

Gene targeting allows precise tailoring of the mouse genome such that desired modifications can be introduced under precise temporal and spatial control. This can be achieved through the use of site-specific recombinases, which mediate deletion or inversion of genomic DNA flanked by recombinase-spec...

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Detalles Bibliográficos
Autores principales: Sangiorgi, Eugenio, Shuhua, Zhang, Capecchi, Mario R.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582622/
https://www.ncbi.nlm.nih.gov/pubmed/18829714
http://dx.doi.org/10.1093/nar/gkn627