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In vivo evaluation of PhiC31 recombinase activity using a self-excision cassette
Gene targeting allows precise tailoring of the mouse genome such that desired modifications can be introduced under precise temporal and spatial control. This can be achieved through the use of site-specific recombinases, which mediate deletion or inversion of genomic DNA flanked by recombinase-spec...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582622/ https://www.ncbi.nlm.nih.gov/pubmed/18829714 http://dx.doi.org/10.1093/nar/gkn627 |