Cargando…

A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs

In humans a single species of the RNAseIII enzyme Dicer processes both microRNA precursors into miRNAs and long double-stranded RNAs into small interfering RNAs (siRNAs). An interesting but poorly understood domain of the mammalian Dicer protein is the N-terminal helicase-like domain that possesses...

Descripción completa

Detalles Bibliográficos
Autores principales:	Soifer, Harris S., Sano, Masayuki, Sakurai, Kumi, Chomchan, Pritsana, Sætrom, Pål, Sherman, Mark A., Collingwood, Michael A., Behlke, Mark A., Rossi, John J.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582626/ https://www.ncbi.nlm.nih.gov/pubmed/18927112 http://dx.doi.org/10.1093/nar/gkn687

Ejemplares similares

A role for human Dicer in pre-RISC loading of siRNAs
por: Sakurai, Kumi, et al.
Publicado: (2011)

Dicer-independent processing of short hairpin RNAs
por: Liu, Ying Poi, et al.
Publicado: (2013)

Analysis of microRNA turnover in mammalian cells following Dicer1 ablation
por: Gantier, Michael P., et al.
Publicado: (2011)

Molecular basis for improved gene silencing by Dicer substrate interfering RNA compared with other siRNA variants
por: Snead, Nicholas M., et al.
Publicado: (2013)

Dual functional BAFF receptor aptamers inhibit ligand-induced proliferation and deliver siRNAs to NHL cells
por: Zhou, Jiehua, et al.
Publicado: (2013)

Insights into the structure and RNA-binding specificity of Caenorhabditis elegans Dicer-related helicase 3 (DRH-3)
por: Li, Kuohan, et al.
Publicado: (2021)

Interplay between HIV-1 infection and host microRNAs
por: Sun, Guihua, et al.
Publicado: (2012)

Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides
por: Lennox, Kim A., et al.
Publicado: (2016)

Combinatorial delivery of small interfering RNAs reduces RNAi efficacy by selective incorporation into RISC
por: Castanotto, Daniela, et al.
Publicado: (2007)

Hairpins under tension: RNA versus DNA
por: Bercy, Mathilde, et al.
Publicado: (2015)

Muscleblind-like 1 interacts with RNA hairpins in splicing target and pathogenic RNAs
por: Yuan, Yuan, et al.
Publicado: (2007)

Hairpin ribozyme-antisense RNA constructs can act as molecular lassos
por: Dallas, Anne, et al.
Publicado: (2008)

Design of extended short hairpin RNAs for HIV-1 inhibition
por: Liu, Ying Poi, et al.
Publicado: (2007)

Probing the structural hierarchy and energy landscape of an RNA T-loop hairpin
por: Zhuang, Zhuoyun, et al.
Publicado: (2007)

Modified dsRNAs that are not processed by Dicer maintain potency and are incorporated into the RISC
por: Salomon, William, et al.
Publicado: (2010)

The terminal loop region controls microRNA processing by Drosha and Dicer
por: Zhang, Xiaoxiao, et al.
Publicado: (2010)

Nucleotide sequence of miRNA precursor contributes to cleavage site selection by Dicer
por: Starega-Roslan, Julia, et al.
Publicado: (2015)

Destabilization of the TAR hairpin affects the structure and function of the HIV-1 leader RNA
por: Vrolijk, Martine M., et al.
Publicado: (2008)

Competitive folding of anti-terminator/terminator hairpins monitored by single molecule FRET
por: Clerte, Caroline, et al.
Publicado: (2013)

Functional polarity is introduced by Dicer processing of short substrate RNAs
por: Rose, Scott D., et al.
Publicado: (2005)

Dissecting the interactions of SERRATE with RNA and DICER-LIKE 1 in Arabidopsis microRNA precursor processing
por: Iwata, Yuji, et al.
Publicado: (2013)

Rbfox proteins regulate microRNA biogenesis by sequence-specific binding to their precursors and target downstream Dicer
por: Chen, Yu, et al.
Publicado: (2016)

The role of deadenylation in the degradation of unstable mRNAs in trypanosomes
por: Schwede, Angela, et al.
Publicado: (2009)

Mutant CAG repeats of Huntingtin transcript fold into hairpins, form nuclear foci and are targets for RNA interference
por: de Mezer, Mateusz, et al.
Publicado: (2011)

Short-hairpin RNAs delivered by lentiviral vector transduction trigger RIG-I-mediated IFN activation
por: Kenworthy, Rachael, et al.
Publicado: (2009)

Distance constraints between microRNA target sites dictate efficacy and cooperativity
por: Sætrom, Pål, et al.
Publicado: (2007)

Argonaute proteins regulate HIV-1 multiply spliced RNA and viral production in a Dicer independent manner
por: Eckenfelder, Agathe, et al.
Publicado: (2017)

A short motif in Drosophila SECIS Binding Protein 2 provides differential binding affinity to SECIS RNA hairpins
por: Takeuchi, Akiko, et al.
Publicado: (2009)

The conserved 5′ apical hairpin stem loops of bamboo mosaic virus and its satellite RNA contribute to replication competence
por: Chen, Hsin-Chuan, et al.
Publicado: (2012)

Solution structure of a purine rich hexaloop hairpin belonging to PGY/MDR1 mRNA and targeted by antisense oligonucleotides
por: Joli, Flore, et al.
Publicado: (2006)

Two-dimensional combinatorial screening and the RNA Privileged Space Predictor program efficiently identify aminoglycoside–RNA hairpin loop interactions
por: Paul, Dustin J., et al.
Publicado: (2009)

RNA helicase A modulates translation of HIV-1 and infectivity of progeny virions
por: Bolinger, Cheryl, et al.
Publicado: (2010)

The DEAD-box helicase DDX3 supports the assembly of functional 80S ribosomes
por: Geissler, Rene, et al.
Publicado: (2012)

Combined roles of ATP and small hairpin RNA in the activation of RIG-I revealed by solution-based analysis
por: Shah, Neelam, et al.
Publicado: (2018)

The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme
por: Lattmann, Simon, et al.
Publicado: (2011)

The loss of a hydrogen bond: Thermodynamic contributions of a non-standard nucleotide
por: Jolley, Elizabeth A., et al.
Publicado: (2017)

The beta hairpin structure within ribosomal protein S5 mediates interplay between domains II and IV and regulates HCV IRES function
por: Bhat, Prasanna, et al.
Publicado: (2015)

PUMILIO competes with AUF1 to control DICER1 RNA levels and miRNA processing
por: Rajasekaran, Swetha, et al.
Publicado: (2022)

Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells
por: Zhou, Jiehua, et al.
Publicado: (2009)

Endogenous short RNAs generated by Dicer 2 and RNA-dependent RNA polymerase 1 regulate mRNAs in the basal fungus Mucor circinelloides
por: Nicolas, Francisco Esteban, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_juh6dckic3k4skdsoe4huvlvrn