Type IV Secretion-Dependent Activation of Host MAP Kinases Induces an Increased Proinflammatory Cytokine Response to Legionella pneumophila

The immune system must discriminate between pathogenic and nonpathogenic microbes in order to initiate an appropriate response. Toll-like receptors (TLRs) detect microbial components common to both pathogenic and nonpathogenic bacteria, whereas Nod-like receptors (NLRs) sense microbial components in...

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Detalles Bibliográficos
Autores principales: Shin, Sunny, Case, Christopher L., Archer, Kristina A., Nogueira, Catarina V., Kobayashi, Koichi S., Flavell, Richard A., Roy, Craig R., Zamboni, Dario S.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582680/
https://www.ncbi.nlm.nih.gov/pubmed/19043549
http://dx.doi.org/10.1371/journal.ppat.1000220

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