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Deubiquitylating enzymes and disease

Deubiquitylating enzymes (DUBs) can hydrolyze a peptide, amide, ester or thiolester bond at the C-terminus of UBIQ (ubiquitin), including the post-translationally formed branched peptide bonds in mono- or multi-ubiquitylated conjugates. DUBs thus have the potential to regulate any UBIQ-mediated cell...

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Detalles Bibliográficos
Autores principales: Singhal, Shweta, Taylor, Matthew C, Baker, Rohan T
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582804/
https://www.ncbi.nlm.nih.gov/pubmed/19007433
http://dx.doi.org/10.1186/1471-2091-9-S1-S3