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Phosphorylation sites in BubR1 that regulate kinetochore attachment, tension, and mitotic exit
BubR1 kinase is essential for the mitotic checkpoint and also for kinetochores to establish microtubule attachments. In this study, we report that BubR1 is phosphorylated in mitosis on four residues that differ from sites recently reported to be phosphorylated by Plk1 (Elowe, S., S. Hummer, A. Uldsc...
Autores principales: | Huang, Haomin, Hittle, James, Zappacosta, Francesca, Annan, Roland S., Hershko, Avram, Yen, Timothy J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582891/ https://www.ncbi.nlm.nih.gov/pubmed/19015317 http://dx.doi.org/10.1083/jcb.200805163 |
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