HP1-β is required for development of the cerebral neocortex and neuromuscular junctions

HP1 proteins are thought to be modulators of chromatin organization in all mammals, yet their exact physiological function remains unknown. In a first attempt to elucidate the function of these proteins in vivo, we disrupted the murine Cbx1 gene, which encodes the HP1-β isotype, and show that the Cb...

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Detalles Bibliográficos
Autores principales: Aucott, Rebecca, Bullwinkel, Jörn, Yu, Yang, Shi, Wei, Billur, Mustafa, Brown, Jeremy P., Menzel, Ursula, Kioussis, Dimitris, Wang, Guozheng, Reisert, Ingrid, Weimer, Jörg, Pandita, Raj K., Sharma, Girdhar G., Pandita, Tej K., Fundele, Reinald, Singh, Prim B.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582898/
https://www.ncbi.nlm.nih.gov/pubmed/19015315
http://dx.doi.org/10.1083/jcb.200804041

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