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VHL Type 2B Mutations Retain VBC Complex Form and Function

BACKGROUND: von Hippel-Lindau disease is characterized by a spectrum of hypervascular tumors, including renal cell carcinoma, hemangioblastoma, and pheochromocytoma, which occur with VHL genotype-specific differences in penetrance. VHL loss causes a failure to regulate the hypoxia inducible factors...

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Detalles Bibliográficos
Autores principales:	Hacker, Kathryn E., Lee, Caroline Martz, Rathmell, W. Kimryn
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583047/ https://www.ncbi.nlm.nih.gov/pubmed/19030229 http://dx.doi.org/10.1371/journal.pone.0003801

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