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GEF-H1 Mediated Control of NOD1 Dependent NF-κB Activation by Shigella Effectors

Shigella flexneri has evolved the ability to modify host cell function with intracellular active effectors to overcome the intestinal barrier. The detection of these microbial effectors and the initiation of innate immune responses are critical for rapid mucosal defense activation. The guanine nucle...

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Detalles Bibliográficos
Autores principales: Fukazawa, Atsuko, Alonso, Carmen, Kurachi, Kiyotaka, Gupta, Sonal, Lesser, Cammie F., McCormick, Beth Ann, Reinecker, Hans-Christian
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583055/
https://www.ncbi.nlm.nih.gov/pubmed/19043560
http://dx.doi.org/10.1371/journal.ppat.1000228