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GEF-H1 Mediated Control of NOD1 Dependent NF-κB Activation by Shigella Effectors
Shigella flexneri has evolved the ability to modify host cell function with intracellular active effectors to overcome the intestinal barrier. The detection of these microbial effectors and the initiation of innate immune responses are critical for rapid mucosal defense activation. The guanine nucle...
Autores principales: | Fukazawa, Atsuko, Alonso, Carmen, Kurachi, Kiyotaka, Gupta, Sonal, Lesser, Cammie F., McCormick, Beth Ann, Reinecker, Hans-Christian |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583055/ https://www.ncbi.nlm.nih.gov/pubmed/19043560 http://dx.doi.org/10.1371/journal.ppat.1000228 |
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