Model-guided design of ligand-regulated RNAi for programmable control of gene expression

Progress in constructing biological networks will rely on the development of more advanced components that can be predictably modified to yield optimal system performance. We have engineered an RNA-based platform, which we call an shRNA switch, that provides for integrated ligand control of RNA inte...

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Detalles Bibliográficos
Autores principales: Beisel, Chase L, Bayer, Travis S, Hoff, Kevin G, Smolke, Christina D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583087/
https://www.ncbi.nlm.nih.gov/pubmed/18956013
http://dx.doi.org/10.1038/msb.2008.62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583087/
https://www.ncbi.nlm.nih.gov/pubmed/18956013
http://dx.doi.org/10.1038/msb.2008.62

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