Cargando…
Telomerase reverse transcriptase haploinsufficiency and telomere length in individuals with 5p– syndrome
Telomerase, which maintains the ends of chromosomes, consists of two core components, the telomerase reverse transcriptase (TERT) and the telomerase RNA (TERC). Haploinsufficiency for TERC or TERT leads to progressive telomere shortening and autosomal dominant dyskeratosis congenita (DC). The clinic...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583393/ https://www.ncbi.nlm.nih.gov/pubmed/17875000 http://dx.doi.org/10.1111/j.1474-9726.2007.00324.x |