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To bind or not to bind – how to down-regulate target genes by liganded thyroid hormone receptor?
The terrain is well explored regarding genes whose gene expression is up-regulated upon binding of thyroid hormone (TH) to its nuclear receptor. This regulation mechanism has been intensively studied and is well understood. In contrast, a lot of white spots remain on the map when it comes to target...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583983/ https://www.ncbi.nlm.nih.gov/pubmed/19014660 http://dx.doi.org/10.1186/1756-6614-1-4 |