High-efficiency Rosa26 knock-in vector construction for Cre-regulated overexpression and RNAi

INTRODUCTION: Rosa26 is a genomic mouse locus commonly used to knock-in cDNA constructs for ubiquitous or conditional gene expression in transgenic mice. However, the vectors generally used to generate Rosa26 knock-in constructs show instability problems, which have a severe impact on the efficiency...

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Detalles Bibliográficos
Autores principales: Hohenstein, Peter, Slight, Joan, Ozdemir, Derya Deniz, Burn, Sally F, Berry, Rachel, Hastie, Nicholas D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2583990/
https://www.ncbi.nlm.nih.gov/pubmed/19014667
http://dx.doi.org/10.1186/1755-8417-1-3

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