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Antisense inhibition of ATM gene enhances the radiosensitivity of head and neck squamous cell carcinoma in mice

BACKGROUND: Treatment failure after radiotherapy of head and neck squamous cell carcinoma (HNSCC) could be a significant problem. Our objective is to sensitize SCCVII cells to ionizing radiation in vitro and in vivo through inhibiting ATM expression using antisense oligodeoxynucleotides (AS-ODNs), a...

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Detalles Bibliográficos
Autores principales:	Zou, Jian, Qiao, Xiaoming, Ye, Huiping, Yang, Yuqiong, Zheng, Xuelian, Zhao, Houyu, Liu, Shixi
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584003/ https://www.ncbi.nlm.nih.gov/pubmed/18950535 http://dx.doi.org/10.1186/1756-9966-27-56

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