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Selective translational repression of HIV-1 RNA by Sam68DeltaC occurs by altering PABP1 binding to unspliced viral RNA

HIV-1 structural proteins are translated from incompletely spliced 9 kb and 4 kb mRNAs, which are transported to the cytoplasm by Crm1. It has been assumed that once in the cytoplasm, translation of incompletely spliced HIV-1 mRNAs occurs in the same manner as host mRNAs. Previous analyses have demo...

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Detalles Bibliográficos
Autores principales:	Marsh, Kim, Soros, Vanessa, Cochrane, Alan
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584037/ https://www.ncbi.nlm.nih.gov/pubmed/18957126 http://dx.doi.org/10.1186/1742-4690-5-97

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