HC-030031, a TRPA1 selective antagonist, attenuates inflammatory- and neuropathy-induced mechanical hypersensitivity

BACKGROUND: Safe and effective treatment for chronic inflammatory and neuropathic pain remains a key unmet medical need for many patients. The recent discovery and description of the transient receptor potential family of receptors including TRPV1 and TRPA1 has provided a number of potential new the...

Descripción completa

Detalles Bibliográficos
Autores principales: Eid, Samer R, Crown, Eric D, Moore, Eric L, Liang, Hongyu A, Choong, Kar-Chan, Dima, Shelley, Henze, Darrell A, Kane, Stefanie A, Urban, Mark O
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584039/
https://www.ncbi.nlm.nih.gov/pubmed/18954467
http://dx.doi.org/10.1186/1744-8069-4-48

Ejemplares similares

Ejemplares similares