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Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease

BACKGROUND: In previous work, we investigated dieldrin cytotoxicity and signaling cell death mechanisms in dopaminergic PC12 cells. Dieldrin has been reported to be one of the environmental factors correlated with Parkinson's disease and may selectively destroy dopaminergic neurons. METHODS: He...

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Detalles Bibliográficos
Autores principales:	Kanthasamy, Anumantha G, Kitazawa, Masashi, Yang, Yongjie, Anantharam, Vellareddy, Kanthasamy, Arthi
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584097/ https://www.ncbi.nlm.nih.gov/pubmed/18945348 http://dx.doi.org/10.1186/1756-6606-1-12

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