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Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes

OBJECTIVE—To establish the mechanism of the phenotypic switch of adipose tissue macrophages (ATMs) from an alternatively activated (M2a) to a classically activated (M1) phenotype with obesity. RESEARCH DESIGN AND METHODS—ATMs from lean and obese (high-fat diet–fed) C57Bl/6 mice were analyzed by a co...

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Detalles Bibliográficos
Autores principales:	Lumeng, Carey N., DelProposto, Jennifer B., Westcott, Daniel J., Saltiel, Alan R.
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Obesity Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584129/ https://www.ncbi.nlm.nih.gov/pubmed/18829989 http://dx.doi.org/10.2337/db08-0872

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