Resistance to High-Fat Diet–Induced Obesity but Exacerbated Insulin Resistance in Mice Overexpressing Preadipocyte Factor-1 (Pref-1): A New Model of Partial Lipodystrophy

OBJECTIVE—White adipose tissue is a critical regulator of whole-body glucose metabolism. Preadipocyte factor-1 (Pref-1) is a secreted protein that inhibits adipocyte differentiation, both in vitro and in vivo. In this study, we have investigated the effects of Pref-1 overexpression on whole-body glu...

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Detalles Bibliográficos
Autores principales: Villena, Josep A., Choi, Cheol Soo, Wang, Yuhui, Kim, Sheene, Hwang, Yu-Jin, Kim, Young-Bum, Cline, Gary, Shulman, Gerald I., Sul, Hei Sook
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2008
Materias:
Obesity Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584131/
https://www.ncbi.nlm.nih.gov/pubmed/18835937
http://dx.doi.org/10.2337/db07-1739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584131/
https://www.ncbi.nlm.nih.gov/pubmed/18835937
http://dx.doi.org/10.2337/db07-1739

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