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Combination Therapy With Glucagon-Like Peptide-1 and Gastrin Restores Normoglycemia in Diabetic NOD Mice

OBJECTIVE—Glucagon-like peptide-1 (GLP-1) and gastrin promote pancreatic β-cell function, survival, and growth. Here, we investigated whether GLP-1 and gastrin can restore the β-cell mass and reverse hyperglycemia in NOD mice with autoimmune diabetes. RESEARCH DESIGN AND METHODS—Acutely diabetic NOD...

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Detalles Bibliográficos
Autores principales:	Suarez-Pinzon, Wilma L., Power, Robert F., Yan, Yanhua, Wasserfall, Clive, Atkinson, Mark, Rabinovitch, Alex
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2008
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584134/ https://www.ncbi.nlm.nih.gov/pubmed/18835930 http://dx.doi.org/10.2337/db08-0688

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