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Non-invasive stroke volume assessment in patients with pulmonary arterial hypertension: left-sided data mandatory
BACKGROUND: Cardiovascular Magnetic Resonance (CMR) is an emerging modality in the diagnosis and follow-up of patients with Pulmonary Arterial Hypertension (PAH). Derivation of stroke volume (SV) from the pulmonary flow curves is considered as a standard in this respect. Our aim was to investigate t...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584621/ https://www.ncbi.nlm.nih.gov/pubmed/18986524 http://dx.doi.org/10.1186/1532-429X-10-51 |
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author | Mauritz, Gert-Jan Marcus, J Tim Boonstra, Anco Postmus, Pieter E Westerhof, Nico Vonk-Noordegraaf, Anton |
author_facet | Mauritz, Gert-Jan Marcus, J Tim Boonstra, Anco Postmus, Pieter E Westerhof, Nico Vonk-Noordegraaf, Anton |
author_sort | Mauritz, Gert-Jan |
collection | PubMed |
description | BACKGROUND: Cardiovascular Magnetic Resonance (CMR) is an emerging modality in the diagnosis and follow-up of patients with Pulmonary Arterial Hypertension (PAH). Derivation of stroke volume (SV) from the pulmonary flow curves is considered as a standard in this respect. Our aim was to investigate the accuracy of pulmonary artery (PA) flow for measuring SV. METHODS: Thirty-four PAH patients underwent both CMR and right-sided heart catheterisation. CMR-derived SV was measured by PA flow, left (LV) and right ventricular (RV) volumes, and, in a subset of nine patients also by aortic flow. These SV values were compared to the SV obtained by invasive Fick method. RESULTS: For SV by PA flow versus Fick, r = 0.71, mean difference was -4.2 ml with limits of agreement 26.8 and -18.3 ml. For SV by LV volumes versus Fick, r = 0.95, mean difference was -0.8 ml with limits of agreement of 8.7 and -10.4 ml. For SV by RV volumes versus Fick, r = 0.73, mean difference -0.75 ml with limits of agreement 21.8 and -23.3 ml. In the subset of nine patients, SV by aorta flow versus Fick yielded r = 0.95, while in this subset SV by pulmonary flow versus Fick yielded r = 0.76. For all regression analyses, p < 0.0001. CONCLUSION: In conclusion, SV from PA flow has limited accuracy in PAH patients. LV volumes and aorta flow are to be preferred for the measurement of SV. |
format | Text |
id | pubmed-2584621 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-25846212008-11-19 Non-invasive stroke volume assessment in patients with pulmonary arterial hypertension: left-sided data mandatory Mauritz, Gert-Jan Marcus, J Tim Boonstra, Anco Postmus, Pieter E Westerhof, Nico Vonk-Noordegraaf, Anton J Cardiovasc Magn Reson Research BACKGROUND: Cardiovascular Magnetic Resonance (CMR) is an emerging modality in the diagnosis and follow-up of patients with Pulmonary Arterial Hypertension (PAH). Derivation of stroke volume (SV) from the pulmonary flow curves is considered as a standard in this respect. Our aim was to investigate the accuracy of pulmonary artery (PA) flow for measuring SV. METHODS: Thirty-four PAH patients underwent both CMR and right-sided heart catheterisation. CMR-derived SV was measured by PA flow, left (LV) and right ventricular (RV) volumes, and, in a subset of nine patients also by aortic flow. These SV values were compared to the SV obtained by invasive Fick method. RESULTS: For SV by PA flow versus Fick, r = 0.71, mean difference was -4.2 ml with limits of agreement 26.8 and -18.3 ml. For SV by LV volumes versus Fick, r = 0.95, mean difference was -0.8 ml with limits of agreement of 8.7 and -10.4 ml. For SV by RV volumes versus Fick, r = 0.73, mean difference -0.75 ml with limits of agreement 21.8 and -23.3 ml. In the subset of nine patients, SV by aorta flow versus Fick yielded r = 0.95, while in this subset SV by pulmonary flow versus Fick yielded r = 0.76. For all regression analyses, p < 0.0001. CONCLUSION: In conclusion, SV from PA flow has limited accuracy in PAH patients. LV volumes and aorta flow are to be preferred for the measurement of SV. BioMed Central 2008-11-05 /pmc/articles/PMC2584621/ /pubmed/18986524 http://dx.doi.org/10.1186/1532-429X-10-51 Text en Copyright © 2008 Mauritz et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Mauritz, Gert-Jan Marcus, J Tim Boonstra, Anco Postmus, Pieter E Westerhof, Nico Vonk-Noordegraaf, Anton Non-invasive stroke volume assessment in patients with pulmonary arterial hypertension: left-sided data mandatory |
title | Non-invasive stroke volume assessment in patients with pulmonary arterial hypertension: left-sided data mandatory |
title_full | Non-invasive stroke volume assessment in patients with pulmonary arterial hypertension: left-sided data mandatory |
title_fullStr | Non-invasive stroke volume assessment in patients with pulmonary arterial hypertension: left-sided data mandatory |
title_full_unstemmed | Non-invasive stroke volume assessment in patients with pulmonary arterial hypertension: left-sided data mandatory |
title_short | Non-invasive stroke volume assessment in patients with pulmonary arterial hypertension: left-sided data mandatory |
title_sort | non-invasive stroke volume assessment in patients with pulmonary arterial hypertension: left-sided data mandatory |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584621/ https://www.ncbi.nlm.nih.gov/pubmed/18986524 http://dx.doi.org/10.1186/1532-429X-10-51 |
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