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Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence
BACKGROUND: Cellular senescence is a state reached by normal mammalian cells after a finite number of cell divisions and is characterized by morphological and physiological changes including terminal cell-cycle arrest. The limits on cell division imposed by senescence may play an important role in b...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584625/ https://www.ncbi.nlm.nih.gov/pubmed/19014415 http://dx.doi.org/10.1186/1756-8935-1-6 |