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Structural definition of a conserved neutralization epitope on HIV-1 gp120
The remarkable diversity, glycosylation and conformational flexibility of the human immunodeficiency virus type 1 (HIV-1) envelope (Env), including substantial rearrangement of the gp120 glycoprotein upon binding the CD4 receptor, allow it to evade antibody-mediated neutralization. Despite this comp...
Autores principales: | Zhou, Tongqing, Xu, Ling, Dey, Barna, Hessell, Ann J., Van Ryk, Donald, Xiang, Shi-Hua, Yang, Xinzhen, Zhang, Mei-Yun, Zwick, Michael B., Arthos, James, Burton, Dennis R., Dimitrov, Dimiter S., Sodroski, Joseph, Wyatt, Richard, Nabel, Gary J., Kwong, Peter D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2584968/ https://www.ncbi.nlm.nih.gov/pubmed/17301785 http://dx.doi.org/10.1038/nature05580 |
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