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Interleukin-1beta and tumor necrosis factor-alpha are expressed by different subsets of microglia and macrophages after ischemic stroke in mice

BACKGROUND: Interleukin-1β (IL-1β) and tumor necrosis factor-α (TNF-α) are expressed by microglia and infiltrating macrophages following ischemic stroke. Whereas IL-1β is primarily neurotoxic in ischemic stroke, TNF-α may have neurotoxic and/or neuroprotective effects. We investigated whether IL-1β...

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Detalles Bibliográficos
Autores principales: Clausen, Bettina H, Lambertsen, Kate L, Babcock, Alicia A, Holm, Thomas H, Dagnaes-Hansen, Frederik, Finsen, Bente
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585073/
https://www.ncbi.nlm.nih.gov/pubmed/18947400
http://dx.doi.org/10.1186/1742-2094-5-46

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