Absence of human herpes virus-8 (HHV8) in nephrogenic systemic fibrosis

BACKGROUND: Nephrogenic systemic fibrosis (NSF) is a fibrosing disorder that exhibits CD34 expression in the majority of lesional spindle cells. Several features of NSF bear similarity to Kaposi sarcoma. FINDINGS: Skin lesions procured from two male NSF patients were found to be negative for HHV8 (L...

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Autores principales: O'Donnell, Patrick J, Duke, Wayne H, Pantanowitz, Liron
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Data Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585090/
https://www.ncbi.nlm.nih.gov/pubmed/18799006
http://dx.doi.org/10.1186/1756-0500-1-82
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author O'Donnell, Patrick J
Duke, Wayne H
Pantanowitz, Liron
author_facet O'Donnell, Patrick J
Duke, Wayne H
Pantanowitz, Liron
author_sort O'Donnell, Patrick J
collection PubMed
description BACKGROUND: Nephrogenic systemic fibrosis (NSF) is a fibrosing disorder that exhibits CD34 expression in the majority of lesional spindle cells. Several features of NSF bear similarity to Kaposi sarcoma. FINDINGS: Skin lesions procured from two male NSF patients were found to be negative for HHV8 (LNA-1) by means of immunohistochemsitry. CONCLUSION: This finding negates a role for HHV8 in the pathogenesis of NSF.
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spelling pubmed-25850902008-11-20 Absence of human herpes virus-8 (HHV8) in nephrogenic systemic fibrosis O'Donnell, Patrick J Duke, Wayne H Pantanowitz, Liron BMC Res Notes Data Note BACKGROUND: Nephrogenic systemic fibrosis (NSF) is a fibrosing disorder that exhibits CD34 expression in the majority of lesional spindle cells. Several features of NSF bear similarity to Kaposi sarcoma. FINDINGS: Skin lesions procured from two male NSF patients were found to be negative for HHV8 (LNA-1) by means of immunohistochemsitry. CONCLUSION: This finding negates a role for HHV8 in the pathogenesis of NSF. BioMed Central 2008-09-17 /pmc/articles/PMC2585090/ /pubmed/18799006 http://dx.doi.org/10.1186/1756-0500-1-82 Text en Copyright © 2008 Pantanowitz et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Data Note
O'Donnell, Patrick J
Duke, Wayne H
Pantanowitz, Liron
Absence of human herpes virus-8 (HHV8) in nephrogenic systemic fibrosis
title Absence of human herpes virus-8 (HHV8) in nephrogenic systemic fibrosis
title_full Absence of human herpes virus-8 (HHV8) in nephrogenic systemic fibrosis
title_fullStr Absence of human herpes virus-8 (HHV8) in nephrogenic systemic fibrosis
title_full_unstemmed Absence of human herpes virus-8 (HHV8) in nephrogenic systemic fibrosis
title_short Absence of human herpes virus-8 (HHV8) in nephrogenic systemic fibrosis
title_sort absence of human herpes virus-8 (hhv8) in nephrogenic systemic fibrosis
topic Data Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585090/
https://www.ncbi.nlm.nih.gov/pubmed/18799006
http://dx.doi.org/10.1186/1756-0500-1-82
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AT pantanowitzliron absenceofhumanherpesvirus8hhv8innephrogenicsystemicfibrosis

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